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[Characteristics of human growth hormone produced by genetically engineered mammalian cells]
T Facklam1, F Maillard, D Nguyen
1Ares Serono, Svýcarsko a Laboratore Serono, Svýcarsko.
Abstract:
Saizen is human growth hormone produced by mammalian cells by genetic engineering. It is identical with hypophyseal GH as regards various physical and chemical parameters. A number of tests did not reveal an alien protein at the 1 ppm level, nor the presence of viruses, and the DNA level is below the detection range. According to these results Saizen is a highly purified growth hormone.