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Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...

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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
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Microbicides: information, beliefs, and preferences for insertion.

Beth A Auslander1, Michelle M Perfect, Daniel M Breitkopf

  • 1Department of Pediatrics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-0319, USA. baauslan@utmb.edu

Journal of Women'S Health (2002)
|December 8, 2007
PubMed
Summary

Women expect to get information on microbicides from doctors and pharmacists. They believe factors like menstruation may affect effectiveness and prefer inserting them before intercourse, often with partner involvement.

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Area of Science:

  • Reproductive Health
  • Infectious Disease Prevention
  • Social and Behavioral Science

Background:

  • Microbicides are under development to prevent sexually transmitted infections (STIs) and HIV acquisition.
  • These products are not yet publicly available, necessitating research into user expectations and preferences.

Purpose of the Study:

  • To determine where women would seek information about microbicides.
  • To identify factors women believe may affect microbicide effectiveness.
  • To understand women's anticipated preferences for microbicide use, including timing, location, and partner involvement.

Main Methods:

  • A cross-sectional study involving face-to-face interviews with 126 women aged 18-35 years.
  • Participants were recruited from a gynecology clinic and shown a microbicide surrogate.
  • Data collected via closed-ended questions on demographics, information sources, perceived effectiveness factors, and usage preferences; analyzed using univariate descriptive statistics.

Main Results:

  • Physicians (89%), package inserts (86%), and pharmacists (70%) were the most anticipated information sources.
  • Two-thirds of women believed menstruation or other medications could reduce effectiveness; one-third cited bathing or birth control.
  • Most women preferred pre-intercourse insertion (90%) in the bathroom (73%), with 95% anticipating informing partners and 38% considering partner insertion.

Conclusions:

  • Anticipatory guidance and package inserts should address women's beliefs about factors potentially limiting microbicide effectiveness.
  • Partner involvement is anticipated, thus education and marketing strategies must include partner perspectives and preferences.