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[The "shen" reaction to trauma--an experimental study].

Y Shen1, D Y Kuang, W R Zhang

  • 1Dept. of Constitution, Shanghai College of TCM.

Zhong Xi Yi Jie He Za Zhi = Chinese Journal of Modern Developments in Traditional Medicine
|October 1, 1991
PubMed
Summary

Trauma, such as bone fracture or burn, significantly damages male mouse testes and disrupts sperm production. These injuries primarily affect the pituitary-gonadal axis, indicating trauma

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Area of Science:

  • Reproductive biology
  • Endocrinology
  • Pathology

Context:

  • The traditional concept of "trauma hurts Shen" suggests systemic effects of injury.
  • Understanding the physiological basis of this concept requires investigating trauma's impact on reproductive health.

Purpose:

  • To investigate the effects of trauma (bone fracture and burn) on the male reproductive system in Kunming mice.
  • To elucidate the pathological mechanisms underlying trauma-induced reproductive dysfunction.

Summary:

  • Experimental trauma induced testicular degeneration and disturbed spermatogenesis in male mice.
  • Electron microscopy revealed pituitary gonadotroph cell damage, including granule reduction and degeneration.
  • Pathological changes indicate that trauma primarily impacts the adenohypophysis-gonadal axis.

Impact:

  • Findings suggest that "Shen" in the context of trauma relates to the function of gonadal organs (testes and ovaries).
  • This research provides a potential physiological explanation for traditional beliefs about trauma's effects on reproductive health.

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