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Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Drug Toxicity: Dose-Dependent Reactions01:24

Drug Toxicity: Dose-Dependent Reactions

Drug toxicities can be stratified into pharmacological, pathological, or genotoxic based on their mechanisms. The incidence and severity of these toxicities generally increase with the drug's concentration in the body and exposure time.Pharmacological toxicity is evident when the therapeutic effects of drugs overshoot into adverse reactions in a predictable, dose-dependent manner. Central nervous system (CNS) depression from barbiturates is a classic example, with effects escalating from...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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Published on: August 25, 2014

Maternal and fetal effects from substance use.

William F Rayburn1

  • 1Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, MSC 10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. wrayburn@salud.unm.edu

Clinics in Perinatology
|December 8, 2007
PubMed
Summary

Pregnancies complicated by substance use pose unique challenges. Healthcare providers must address the complex psychologic, social, and legal needs of pregnant women using drugs to ensure optimal fetal and maternal outcomes.

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Area of Science:

  • Obstetrics and Gynecology
  • Addiction Medicine
  • Perinatal Health

Background:

  • Substance use is common in the reproductive age population.
  • Some women do not alter substance use until pregnancy diagnosis, leading to fetal exposure.
  • Care for pregnant women with substance use disorders is complex and demanding.

Purpose of the Study:

  • To discuss issues related to pregnancies complicated by substance use.
  • To highlight the unique needs of substance-using pregnant women.
  • To address the legal and ethical considerations in managing these pregnancies.

Main Methods:

  • Literature review on substance use in pregnancy.
  • Discussion of clinical management challenges.
  • Analysis of psychologic, social, and legal aspects.

Main Results:

  • A significant number of fetuses are exposed to illicit substances in utero.
  • Effective care requires understanding unique patient needs.
  • Legal and ethical ramifications are critical considerations.

Conclusions:

  • Managing pregnancies with substance use requires a comprehensive approach.
  • Healthcare providers need specialized knowledge and sensitivity.
  • Addressing psychosocial and legal factors is essential for patient care.