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Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management

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Entirely polytetrafluoroethylene coating for pacemaker system contact dermatitis.

Akinori Tamenishi¹, Akihiko Usui, Hideki Oshima

¹Department of Cardiothoracic Surgery, Nagoya University Hospital, P.O. Box 466-0065, 65 Tsurumai-cho, Syouwa, Nagoya, Aichi, Japan. tamenisi@med.nagoya-u.ac.jp

Interactive Cardiovascular and Thoracic Surgery

|December 8, 2007

Summary

Pacemaker system contact dermatitis caused skin necrosis, requiring multiple re-implantations. Coating the new system with polytetrafluoroethylene (PTFE) sheets successfully resolved the allergy, preventing recurrence.

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Area of Science:

Cardiology
Allergy and Immunology
Biomaterials Science

Background:

Pacemaker implantation is a common procedure for treating cardiac arrhythmias.
Adverse reactions to implanted electronic devices, such as contact dermatitis, can necessitate revision surgeries.
Complete atrio-ventricular block requires reliable cardiac pacing.

Observation:

A 63-year-old male patient developed recurrent skin necrosis at the pacemaker generator site.
Multiple re-implantations of the pacemaker system were performed due to the necrosis.
Skin patch testing revealed hypersensitivity to multiple components of the pacemaker system.

Findings:

The patient's pacemaker system was removed and replaced with a new system coated in polytetrafluoroethylene (PTFE) sheets.
The PTFE coating covered both the leads and the generator.
Following the re-implantation with PTFE-coated components, the patient experienced no recurrence of skin necrosis or allergic reaction.

Implications:

Polytetrafluoroethylene (PTFE) sheet coating demonstrates efficacy in managing pacemaker system contact dermatitis.
This biomaterial coating offers a potential solution for patients with hypersensitivity to standard pacemaker components.
Further research into biocompatible coatings for implantable electronic devices is warranted to improve patient outcomes.