Accuracy of growth hormone measurements

The availability of high quality reagents and new methodology have contributed to overall improvements in the performance of immunoassays of human growth hormone in recent years. Discrepancies between superficially similar methods do occur as a result of the heterogeneous nature of the hormone itself. However, there is also evidence of incorrect standardisation in widely used, commercially available assays. Careful interpretation of growth hormone assays is still required, therefore, especially when results from different laboratories are being compared.