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Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
Published on: June 7, 2020
Estrogen-like activities in Vitex species from China determined by a cell based proliferation assay
1Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai, China.
Die Pharmazie
|December 11, 2007
Abstract:
Ethanolic extracts of four Chinese medicinally used Vitex species were selected and tested for their estrogen-like activities, using an ERalpha-positive MCF-7 cell based proliferation assay (E-screen assay) and cell cycle analysis (flow cytometry). Vitex negundo displayed the highest estrogenic-like activity, and could be useful in hormone replacement therapy (HRT).
