[Pineapple juice as a negative oral contrast agent in magnetic resonance cholangiopancreatography]

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L Arrivé1, C Coudray, L Azizi

  • 1Service de radiologie, Assistance-Publique-Hôpitaux de Paris, Faculté de Médecine Pierre et Marie Curie, Hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75012 Paris. lionel.arrive@sat.ap-hop-paris.fr

Journal De Radiologie
|December 11, 2007
PubMed
Abstract

Insights

Pineapple juice effectively suppresses gastrointestinal signal on magnetic resonance cholangiopancreatography (MRCP) scans, comparable to traditional agents. Choose brands with high manganese for optimal results in MRCP imaging.

Area of Science:

  • Radiology
  • Medical Imaging
  • Gastroenterology

Background:

  • Magnetic resonance cholangiopancreatography (MRCP) image quality is often compromised by high gastrointestinal signal on T2-weighted images.
  • Effective oral negative contrast agents are needed to improve MRCP diagnostic accuracy.

Purpose of the Study:

  • To evaluate pineapple juice (PJ) as a potential oral negative contrast agent for MRCP.
  • To compare the efficacy of PJ with a standard paramagnetic contrast agent (ferumoxsil).

Main Methods:

  • MRCPs were performed on 100 patients (50 with PJ, 50 with ferumoxsil).
  • Image quality, including signal suppression and ductal visualization, was assessed by blinded reviewers.
  • In vitro analysis correlated PJ signal intensity with manganese concentration.
  • Taste comparison between PJ and ferumoxsil was conducted.

Main Results:

  • Pineapple juice demonstrated comparable signal suppression in the stomach, duodenum, and small bowel to ferumoxsil.
  • Visualization of the pancreatic and biliary ducts was similar between the two agents.
  • PJ's signal intensity correlated with manganese concentration, which varied significantly among brands.
  • Pineapple juice was preferred for taste over ferumoxsil.

Conclusions:

  • Pineapple juice serves as an effective negative oral contrast agent for MRCP, yielding results similar to paramagnetic agents.
  • Selection of PJ brands with high manganese concentration is recommended for optimal performance.
  • The palatable taste of PJ offers a patient-friendly alternative for MRCP contrast enhancement.

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