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New developments of the "lock-in" modified cycloSal-d4TMPs.

Dalibor Vukadinović-Tenter1, Jan Balzarini, Chris Meier

  • 1Department of Chemistry, Organic Chemistry, Faculty of Science, University of Hamburg, Martin Luther King-Platz 6, 20146 Hamburg, Germany.

Nucleosides, Nucleotides & Nucleic Acids
|December 11, 2007
PubMed
Summary

New cycloSal-d4TMP prodrugs with modified linkers show promise. These compounds exhibit varying hydrolysis rates and potent antiviral activity against HIV, indicating potential therapeutic applications.

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