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Updated: Aug 4, 2026

Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling
Published on: August 19, 2017
[Clinico-morphological characteristics of acute pancreatitis and its complications]
Abstract:
The results of treatment of 6681 patients with acute pancreatitis (AP) were analysed. Operated on were 554 patients with AP, among them, 260-with acute destructive pancreatitis (ADP). Total lethality was 1.6%, the postoperative one-20.2%. In ADP, the postoperative lethality was 28%. Mild forms of the AP course were characterized by constancy of the clinical symptoms and their rapid involution, severe forms of the disease (destructive pancreatitis)--by progressive periodicity and intensity of clinical signs. A morphologic pattern of the different forms of AP is described. It was established that at the early period of the disease, patients died mainly from posthemorrhagic anemia, anemia with intoxication, at the late period--predominantly from different purulent and necrotic complications.
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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