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Updated: Feb 10, 2026

Chemical Triphosphorylation of Oligonucleotides
Published on: June 2, 2022
Reagents for the selective immobilization of oligonucleotides on solid supports
Maksim V Kvach1, Igor A Prokhorenko, Alexey V Ustinov
1Institute of Physical Organic Chemistry NAS, Minsk, Belarus.
Abstract:
New reagents (CPGs and phosphoramidites) for automatic solid phase synthesis of modified oligonucleotides were designed. Three oligonucleotides carrying fluorescent label at the 5'-terminus and an anchor group at the 3'-terminus were prepared and their immobilization in orthogonal conditions on solid supports was studied.
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