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FLT3 internal tandem duplication in low risk MDS: clinical and basic science relevance

Deborah Rund1

  • 1Hematology Department, Hebrew University-Hadassah Hospital, Jerusalem, Israel. rund@cc.huji.ac.il

Leukemia & Lymphoma
|December 11, 2007
PubMed
Abstract

No abstract available in PubMed .

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As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...