[Polyostotic fibrous dysplasia (Jaffe-Lichtenstein)]

Area of Science:

• Orthopedics
• Endocrinology
• Radiology

Background:

• Polyostotic fibrous dysplasia is a rare, non-inherited bone disorder of unknown etiology.
• It typically manifests during puberty and is characterized by chronic progression with potential for long-term remissions.
• The condition can lead to significant skeletal deformities and an increased risk of spontaneous fractures.

Observation:

• The study presents two cases of pelvic polyostotic fibrous dysplasia with progression to the lower extremities.
• Clinical observation highlights the potential for deformities and spontaneous fractures.

Findings:

• Diagnosis relies on comprehensive radiological imaging and histological examination.
• The disease exhibits chronic characteristics with periods of remission lasting several years.

Implications:

• Early diagnosis and monitoring are crucial for managing polyostotic fibrous dysplasia.
• Treatment strategies range from symptomatic and physiatric approaches to surgical interventions for severe cases.