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Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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Vitrectomy for a symptomatic lamellar macular hole.

Bruce R Garretson1, John S Pollack, Alan J Ruby

  • 1Associated Retinal Consultants, Royal Oak, Michigan 48073, USA. bgarretson@msn.com

Ophthalmology
|December 11, 2007
PubMed
Summary

Vitrectomy with internal limiting membrane (ILM) stripping significantly improved vision in most patients with lamellar macular holes (LMH). Surgical intervention for LMH demonstrated positive outcomes in visual acuity and retinal appearance.

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Area of Science:

  • Ophthalmology
  • Retinal Surgery

Background:

  • Lamellar macular holes (LMH) cause central vision loss.
  • Surgical treatment options for LMH require investigation.

Purpose of the Study:

  • To evaluate surgical findings and outcomes of vitrectomy for LMH.
  • To assess the efficacy of internal limiting membrane (ILM) stripping in treating LMH.

Main Methods:

  • Retrospective case series of 27 patients (27 eyes) with LMH.
  • All patients underwent 3-port vitrectomy with ILM stripping.
  • Preoperative and postoperative best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) were analyzed.

Main Results:

  • Visual acuity improved in 93% of patients, with a mean gain of 3.2 Snellen lines.
  • OCT imaging showed improvement or normalization in 92% of analyzed eyes.
  • Vitrectomy with ILM stripping was performed by a single surgeon.

Conclusions:

  • Vitrectomy with ILM stripping is a beneficial treatment for central visual loss due to LMH.
  • The procedure demonstrates positive anatomical and functional outcomes.