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Updated: Jul 9, 2026

09:50
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives
Sherif B Abdel Ghani1, Louise Weaver, Zidan H Zidan
1School of Chemistry, University of Southampton, Southampton SO17 1BJ, UK.
Bioorganic & Medicinal Chemistry Letters
|December 11, 2007
Abstract:
Eleven flavonoid derivatives were synthesised using a modified Baker-Venkataraman rearrangement, and subsequent microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resistant Staphylococcus aureus.

