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Updated: Jul 9, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
Published on: February 17, 2017
Synthesis of new heterocyclic derivatives of alpha,alpha-trehalose
Inácio Luduvico1, Mara R C Couri, Leandro J dos Santos
1Departamento de Química-Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, Belo Horizonte-MG, CEP 31270-901, Brazil. i.luduvico@bol.com.br
Abstract:
Several novel N-1, N-2, and S-5 tetrazole and 1,3,4-oxadiazole derivatives of alpha,alpha-trehalose disubstituted at C-6,6', with potential synthetic and pharmacological interest were prepared from commercial tetrazoles and 1,3,4-oxadiazoles in reaction with hexa-O-benzyl-6,6'-di-O-triflyl-alpha,alpha-trehalose.
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