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Proteomics: clinical applications.

Delfina C Dominguez1, Rosana Lopes, M Lorraine Torres

  • 1University of Texas at El Paso, Clinical Laboratory Science, College of Health Sciences, 1101 N. Campbell Street, El Paso, TX 79902-4238, USA. Delfina@utep.edu

Clinical Laboratory Science : Journal of the American Society for Medical Technology
|December 12, 2007
PubMed
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Proteomics analyzes all proteins to understand disease. Clinical proteomics uses these techniques for new diagnostics, therapeutics, and personalized medicine, improving patient outcomes.

Area of Science:

  • Biochemistry and Molecular Biology
  • Medical Diagnostics

Background:

  • Proteomics, the study of all proteins expressed by a genome, emerged in 1997.
  • Clinical proteomics applies these advanced techniques to the medical field.

Purpose of the Study:

  • To identify proteins implicated in disease pathogenesis.
  • To understand alterations in protein expression due to illness.
  • To explore the potential of clinical proteomics in healthcare.

Main Methods:

  • Utilizes sophisticated techniques such as two-dimensional electrophoresis, imaging, mass spectrometry, and bioinformatics.
  • Focuses on protein identification, quantification, and characterization.

Main Results:

  • Clinical proteomics aids in identifying disease-associated proteins.

Related Experiment Videos

  • It provides insights into how diseases alter protein expression patterns.

    • Conclusions:

    • Clinical proteomics holds significant potential for developing novel diagnostic and prognostic tests.
    • It can identify new therapeutic targets and enable personalized patient treatment strategies.