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Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Development and validation of a noninvasive method to estimate cardiac output using cuff sphygmomanometry
Shiu-Shin Chio1, Jeffrey J Tsai, Yen-Ming Hsu
1Pulse Metric, Inc.
Clinical Cardiology
|December 12, 2007
Summary
Noninvasive cardiac output (CO) estimation using pulse-waveform analysis (PWA) from a brachial cuff shows good correlation with Doppler ultrasound. This PWA method can monitor hemodynamic changes in cardiac patients during routine measurements.
Area of Science:
- Cardiology
- Biomedical Engineering
- Hemodynamics
Background:
- Noninvasive cardiac output (CO) monitoring is crucial for hypertension management.
- Pulse-waveform analysis (PWA) using a brachial cuff sphygmomanometer offers a novel noninvasive CO estimation method.
- This study validates PWA's ability to track CO changes against Doppler ultrasound during dobutamine stimulation.
Purpose of the Study:
- To validate CO estimation by PWA across a wide range of CO levels induced by dobutamine stimulation.
- To assess the correlation between PWA and Doppler ultrasound for CO measurement in cardiac patients.
Main Methods:
- 44 cardiac patients undergoing dobutamine stress echocardiography were enrolled.
- Simultaneous noninvasive CO measurements were obtained using Doppler ultrasound and PWA techniques.
- Data from 207 simultaneous measurements were analyzed using linear regression.
Main Results:
- A strong intra-patient correlation (r = 0.69 to 0.98) was observed between PWA and Doppler CO measurements at varying dobutamine levels.
- Overall correlation between PWA and Doppler CO was high (r = 0.82, p < 0.001).
- The bias was 0.4 L/min with a standard deviation of 1.8 L/min.
Conclusions:
- Noninvasive CO measurement using PWA from a sphygmomanometer correlates well with Doppler ultrasound.
- The PWA method is suitable for monitoring hemodynamic changes in hypertensive and cardiac patients.
- This technique can be integrated into routine blood pressure measurements for enhanced patient monitoring.
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