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[Changes in the continuous electrocardiogram during the exercise stress test in women with angina pectoris and normal
S Djurković-Ivanović1, D Svetković-Pendić
1Institute for Rehabilitation, Belgrade.
Insights
Ischaemic cardiac disease can occur with normal coronary arteries. This study suggests a mixed form of angina pectoris involving vasospasm and prearteriole obstruction in women.
Area of Science:
- Cardiology
- Vascular Biology
- Diagnostic Medicine
Background:
- Ischaemic cardiac disease is typically linked to obstructive coronary arteries.
- However, a subset of patients presents with angina and normal coronary arteries, posing a diagnostic challenge.
Observation:
- Ten female patients (30-40 years old) experiencing angina pectoris with angiographically normal coronary arteries were evaluated.
- Electrocardiographic monitoring during physical stress and Holter monitoring were employed.
Findings:
- The study identified a mixed form of angina pectoris.
- This condition appears to involve both coronary artery vasospasm and obstruction in prearteriolar vessels.
Implications:
- This research highlights the importance of considering non-obstructive causes of angina, particularly vasospasm and microvascular dysfunction.
- Further investigation into these mechanisms is crucial for accurate diagnosis and tailored treatment of ischaemic cardiac disease in women.
Abstract:
Ischaemic cardiac disease is usually diagnosed in patients with obstruent coronary arteries. However, it is also found in subjects with normal coronary arteries. Ten female patients, aged 30-40 years, with angina pectoris and normal coronary findings, were studied. Electrocardiographic changes were studied during physical tests and 24-hour electrocardiography. The findings suggested a mixed form of angina pectoris with both vasospasm and obstruent prearterioles.