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Management of heart failure in elderly people
M Imazio1, A Cotroneo, G Gaschino
1Cardiology Department, Maria Vittoria Hospital, Torino, Italy. massimo_imazio@yahoo.it
Insights
Heart failure (HF) in elderly individuals presents unique challenges due to aging and comorbidities. Management often relies on empiric evidence from younger populations as older adults are typically excluded from clinical trials.
Area of Science:
- Gerontology
- Cardiology
- Internal Medicine
Background:
- Heart failure (HF) is a significant health concern in the elderly population.
- Aging-related physiological changes can predispose individuals to HF and affect their response to illness.
- Elderly patients often present with multiple chronic conditions and geriatric syndromes, complicating HF management.
Purpose of the Study:
- To synthesize current knowledge on the presentation, clinical features, and management of heart failure in older adults.
- To highlight the unique aspects of HF in the elderly and the challenges in its treatment.
- To review the evidence base for HF management in elderly populations.
Main Methods:
- A comprehensive literature search was conducted using multiple evidence-based databases.
- Key databases included Cochrane Database of Systematic Reviews, Clinical Evidence, and MEDLINE.
- Search terms focused on heart failure, elderly populations, and management strategies.
Main Results:
- Aging features and comorbidities significantly impact HF presentation and progression in the elderly.
- Diagnosis can be challenging due to atypical symptoms and overlapping conditions, though diagnostic criteria remain consistent.
- Current drug treatments are largely empirical, mirroring recommendations for younger patients due to trial exclusions.
- Disease management programs show promise in reducing HF morbidity and mortality in older adults.
Conclusions:
- Heart failure is a leading cause of hospitalization and readmission among older adults.
- HF in the elderly is characterized by specific features and frequent comorbidities, imposing a substantial global financial burden.
- The exclusion of elderly individuals from clinical trials necessitates empirical management approaches based on data from younger cohorts.
Aims:
To review currently available knowledge on presentation, clinical features and management of heart failure (HF) in elderly people.
Methods:
To review currently available evidence, we performed a thorough search of several evidence-based sources of information, including Cochrane Database of Systematic Reviews, Clinical Evidence, Evidence-based guidelines from National Guidelines Clearinghouse and a comprehensive MEDLINE search with the MeSH terms: 'heart failure', 'elderly' and 'management'.
Results:
A number of features of ageing may predispose elderly people to HF, and may impair the ability to respond to injuries. Another hallmark of elderly patients is the increasing prevalence of multiple coexisting chronic conditions and geriatric syndromes that may complicate the clinical presentation and evolution of HF. Although diagnosis may be challenging, because atypical symptoms and presentations are common, and comorbid conditions may mimic or complicate the clinical picture, diagnostic criteria do not change in elderly people. Drug treatment is not significantly different from that recommended in younger patients, and largely remains empiric, because clinical trials have generally excluded elderly people and patients with comorbid conditions. Disease management programmes may have the potential to reduce morbidity and mortality for patients with HF.
Conclusions:
Heart failure is the commonest reason for hospitalisation and readmission among older adults. HF shows peculiar features in elderly people, and is usually complicated by comorbidities, presenting a significant financial burden worldwide, nevertheless elderly people have been generally excluded from clinical trials, and thus management largely remains empiric and based on evidence from younger age groups.
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