The incidence of cyclic vomiting syndrome in children: population-based study

Emer Fitzpatrick1, Billy Bourke, Brendan Drumm

  • 1UCD School of Medicine and Medical Science, The Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

Insights

Cyclic vomiting syndrome (CVS) affects children, with an incidence of 3.15 per 100,000 annually in Ireland. This condition often begins in early childhood, causing significant illness and missed school days.

Area of Science:

  • Pediatric Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent, severe vomiting episodes in children.
  • Population-based incidence data for pediatric CVS has been lacking.
  • Understanding CVS incidence and clinical features is crucial for diagnosis and management.

Purpose of the Study:

  • To determine the population-based incidence of cyclic vomiting syndrome (CVS) in children in Ireland.
  • To describe the clinical characteristics of pediatric CVS at the time of diagnosis.

Main Methods:

  • A nationwide survey of all pediatricians in Ireland was conducted over one year (2005).
  • The Irish Pediatric Surveillance Unit (IPSU) collected monthly reports of incident CVS cases based on established criteria.
  • Demographic and clinical data were anonymously gathered from reporting physicians.

Main Results:

  • The incidence of CVS in Ireland was determined to be 3.15 per 100,000 children annually.
  • The median age at onset was 4 years, with 46% of cases starting by age 3.
  • Affected children experienced a median of 8 episodes per year, with 85% missing school and 44% requiring hospitalization.

Conclusions:

  • Pediatric cyclic vomiting syndrome (CVS) is a relatively common condition, with an incidence comparable to other childhood gastrointestinal diseases.
  • CVS typically begins in early childhood and leads to significant morbidity.
  • Early diagnosis and management are essential for affected children.
Abstract

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