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Prognostic significance of thin-section CT scan findings in small-sized lung adenocarcinoma
Toshihiko Hashizume1, Kouzo Yamada, Naoyuki Okamoto
1Yamato City Hospital, Department of Respiratory Medicine, Fukami-nishi 8-3-6, Yamato-city, Kanagawa, 242-8602 Japan. toshi@yk9.so-net.ne.jp
Objectives:
The purpose of this study is to evaluate the prognostic importance of thin-section (TS) CT scan findings in small-sized lung adenocarcinomas.
Patients And Methods:
We reviewed TS-CT scan findings and pathologic specimens from 359 consecutive patients who underwent surgical resection for peripheral lung adenocarcinomas
Results:
No pathologic invasive findings or recurrence were found in patients with air-containing-type tumors. Pathologic invasive findings and recurrence were found in 10 to 30% of patients with solid-density-type tumors. The air-containing type tumors seen on TS-CT scans and Noguchi type A or B tumors were demonstrated as prognostic factors for good outcome by chi2 test (p < 0.001). Multivariate analyses revealed lymphatic permeation as a significant prognostic factor.
Conclusion:
The TS-CT scan findings were important predictive factors for postsurgical outcome in patients with lung adenocarcinoma.
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