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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Trends in prostate-specific antigen testing from 1995 through 2004.

Wildon R Farwell1, Jeffrey A Linder, Ashish K Jha

  • 1Veterans Affairs Boston Healthcare System, Boston Division, Boston, MA 02130, USA. Wildon.Farwell@va.gov

Archives of Internal Medicine
|December 12, 2007
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This summary is machine-generated.

Prostate-specific antigen (PSA) testing for prostate cancer screening has significantly increased in primary care settings from 1995 to 2004. This rise occurred despite a lack of clear evidence of benefit, particularly in younger and Black men.

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Area of Science:

  • Urology
  • Public Health
  • Preventive Medicine

Background:

  • The clinical utility of prostate-specific antigen (PSA) testing for prostate cancer screening remains a subject of ongoing debate.
  • Changes in PSA testing rates during this period of controversy have not been well-documented.

Purpose of the Study:

  • To analyze trends in PSA testing rates among primary care providers in the United States.
  • To investigate whether PSA testing has changed during the period of controversy regarding its utility.

Main Methods:

  • Utilized data from the National Ambulatory Medical Care Survey (1995-2004).
  • Focused on visits by healthy men aged 35 years and older to primary care providers.
  • Compared PSA testing rates between 1995-1999 and 2000-2004, examining overall and subgroup trends.

Main Results:

  • PSA test orders increased from 4.7% of visits in 1995 to 7.0% in 2004 (P = .03).
  • Annual odds of PSA testing increased by 8% (OR, 1.08; P < .001) from 1995-2004.
  • Significant increases were observed in general medical examinations, among Black men (OR, 2.3), and younger men aged 35-49 (OR, 1.8).

Conclusions:

  • PSA testing for prostate cancer screening has increased dramatically in a nationally representative sample.
  • This increase occurred despite a lack of clear evidence supporting its benefit.
  • The rise was particularly pronounced in Black men and younger men, highlighting potential disparities in screening practices.