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The multifaceted role of Notch in cardiac development and disease

Frances A High1, Jonathan A Epstein

  • 1Department of Cell and Developmental Biology and the Cardiovascular Institute, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.

Nature Reviews. Genetics
|December 12, 2007
PubMed

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The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Notch Signaling Pathway03:14

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