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Related Experiment Video

Updated: Jul 9, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

MR urography evaluation of obstructive uropathy.

J Damien Grattan-Smith¹, Stephen B Little, Richard A Jones

¹Department of Radiology, Children's Healthcare of Atlanta, Emory University School of Medicine, 1001 Johnson Ferry Road, Atlanta, GA 30342, USA. Damien.grattan-smith@choa.org

Pediatric Radiology

|December 12, 2007

Summary

MR urography effectively evaluates obstructive uropathy in children by combining anatomic and functional imaging. This method assesses kidney function and parenchyma quality, aiding surgical intervention decisions.

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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Area of Science:

Pediatric Radiology
Urology
Medical Imaging

Background:

Hydronephrosis and obstructive uropathy are common indications for MR urography in pediatric patients.
Patients often include infants with antenatal hydronephrosis and older children with abdominal pain, hematuria, or urinary tract infections.
Urinary obstruction in children is frequently chronic and partial, leading to intermittent pressure increases.

Purpose of the Study:

To evaluate the utility of MR urography in assessing obstructive uropathy in pediatric patients.
To combine anatomic and functional information for a comprehensive evaluation of hydronephrosis.
To provide prognostic information and aid in selecting patients for surgical intervention.

Main Methods:

MR urography utilizes a fluid and diuretic challenge to assess hydronephrotic kidneys.
High-quality anatomic images provide morphologic assessment.
Functional parameters include renal transit time (RTT), signal intensity changes post-contrast, calyceal transit time, and differential renal function (vDRF-pDRF).

Main Results:

MR urography provides a morphologic assessment of the hydronephrotic system.
Delayed RTT and urine-contrast levels indicate urinary stasis.
Hydronephrotic systems are classified as compensated or decompensated based on parenchymal signal intensity changes.

Conclusions:

MR urography offers a comprehensive evaluation of obstructive uropathy by integrating anatomic and functional data.
The technique assesses renal parenchyma quality and provides prognostic information.
This imaging modality can assist in identifying pediatric patients who may benefit from surgical intervention.