Related Experiment Video
Updated: Jul 9, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
MR features of isolated uterine relapse in an adolescent with acute lymphoblastic leukaemia
Sébastien Novellas1, Maude Fournol, Anne Deville
1Medical Imaging Service, Archet 2 Hospital, Regional Hospital Centre and University of Nice, 151 route de Saint Antoine de Ginestière, B.P. 3079, 06202, Nice Cedex 3, France. novellas.s@chu-nice.fr
Abstract:
Relapses of lymphoblastic leukaemia traditionally involve the central nervous system and testes in boys. Involvement of the female pelvic organs is frequently found at autopsy; however, involvement of the cervical uterus is rare and even less commonly symptomatic. A 13-cm uterine mass was discovered in a 15-year-old adolescent with a history of lymphoblastic leukaemia during childhood. Pelvic MRI was the best tool to assess the size, characteristics and invasive nature of this lesion of the uterine cervix. To our knowledge, this is a unique case in that we describe the MRI appearance of a relapsing lymphoblastic leukaemic mass both before and after treatment.
