Multiple intracranial tuberculomas in an HIV-negative 28 year old male--a case report

Intracranial tuberculomas are uncommon complications of tuberculosis, especially in immuno-competent individuals with no evidence of extra-cranial foci. We report a case of an HIV- negative young male who presented with presumed cerebral and cerebellar tuberculomas without identifiable extra-cranial focus. The CT scan revealed multiple intracranial ring-enhanced lesions. The remarkable response to antituberculous drugs and steroid (prednisolone) with near complete resolution of clinical and radiological signs was highly suggestive of diagnosis. In the differential diagnosis of intracranial mass lesions in sub-Saharan Africa, a high index of clinical suspicion is needed to avoid misdiagnosis of intracranial tuberculoma.