Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

5S rRNA: Structure and Function from Head to Toe.

Jonathan D Dinman1

  • 1Department of Cell Biology and Molecular Genetics, Microbiology Building Room 2135, University of Maryland, College Park, MD 20742.

International Journal of Biomedical Science : IJBS
|December 13, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Translon: a single term for translated regions.

Nature methods·2025
Same author

Plasticity of the mammalian integrated stress response.

Nature·2025
Same author

RETRACTED: Dahal et al. PERK Is Critical for Alphavirus Nonstructural Protein Translation. <i>Viruses</i> 2021, <i>13</i>, 892.

Viruses·2025
Same author

Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR).

Nature structural & molecular biology·2025
Same author

Shiftless Is a Novel Member of the Ribosome Stress Surveillance Machinery That Has Evolved to Play a Role in Innate Immunity and Cancer Surveillance.

Viruses·2023
Same author

Correction: A novel de novo variant in CASK causes a severe neurodevelopmental disorder that masks the phenotype of a novel de novo variant in EEF2.

Journal of human genetics·2023
Same journal

Nitric Oxide on Pathophysiology of SARS-CoV 19: Toward Possible Role of Acupuncture Treatment.

International journal of biomedical science : IJBS·2022
Same journal

Successful Myomectomy during Cesarean Section: Case Report & Literature Review.

International journal of biomedical science : IJBS·2017
Same journal

The Impact of Biophysical Properties of Erythrocytes on their Aggregation.

International journal of biomedical science : IJBS·2017
Same journal

To Evaluate Effect of Airborne Particle Abrasion using Different Abrasives Particles and Compare Two Commercial Available Zirconia on Flexural Strength on Heat Treatment.

International journal of biomedical science : IJBS·2017
Same journal

Passionflower Extract Induces High-amplitude Rhythms without Phase Shifts in the Expression of Several Circadian Clock Genes <i>in Vitro</i> and <i>in Vivo</i>.

International journal of biomedical science : IJBS·2017
Same journal

Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women.

International journal of biomedical science : IJBS·2017
See all related articles

The 5S ribosomal RNA (rRNA) connects all ribosome functional centers. This study details how 5S rRNA transmits information to coordinate ribosomal functions using structural and genetic data.

Area of Science:

  • Molecular Biology
  • Structural Biology
  • Genetics

Background:

  • The 5S ribosomal RNA (rRNA) is centrally located within the ribosome.
  • It is hypothesized to act as a physical transducer, mediating communication between ribosomal functional centers.
  • Understanding its role is crucial for deciphering ribosome function.

Purpose of the Study:

  • To synthesize structural and genetic data concerning 5S rRNA.
  • To elucidate the detailed mechanism by which 5S rRNA coordinates ribosomal functions.
  • To provide a comprehensive model of 5S rRNA's role in information transmission.

Main Methods:

  • Integration of existing structural data of the ribosome.
  • Analysis of genetic information related to 5S rRNA and ribosomal function.

Related Experiment Videos

  • Comparative analysis across different ribosomal states.

    • Main Results:

    • Detailed structural mapping of 5S rRNA interactions within the ribosome.
    • Identification of key regions in 5S rRNA involved in inter-center communication.
    • Correlation of structural insights with genetic observations of ribosomal activity.

    Conclusions:

    • 5S rRNA plays a critical role in linking and coordinating all ribosomal functional centers.
    • Structural and genetic evidence supports 5S rRNA as a key information transducer.
    • This work provides a refined model for 5S rRNA-mediated ribosomal coordination.