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Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Brain perfusion CT: principles, technique and clinical applications.

A Cianfoni1, C Colosimo, M Basile

  • 1Dipartimento di Bio-immagini e Scienze Radiologiche, Sezione di Radiodiagnostica, Università Cattolica del Sacro Cuore, Policlinico A. Gemelli, Largo Gemelli 8, Rome, Italy. acianfoni@hotmail.com

La Radiologia Medica
|December 13, 2007
PubMed
Summary

Dynamic perfusion CT (p-CT) offers fast, reliable brain imaging for cerebral blood flow and volume. It

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Area of Science:

  • Neuroimaging
  • Radiology
  • Cerebrovascular Medicine

Background:

  • Brain haemodynamics imaging is gaining interest.
  • Dynamic perfusion computed tomography (p-CT) provides quantitative measurements of cerebral blood flow (CBF) and cerebral blood volume (CBV).
  • p-CT aids in visualizing cerebral autoregulation mechanisms.

Purpose of the Study:

  • To illustrate the principles, technique, and clinical applications of p-CT cerebral perfusion studies.
  • To highlight p-CT's utility in assessing cerebral perfusion.
  • To explore p-CT's role in various cerebrovascular conditions.

Main Methods:

  • Utilizes dynamic perfusion computed tomography (p-CT) for imaging.
  • Involves quantitative measurements of cerebral blood flow (CBF) and cerebral blood volume (CBV).
  • Combines p-CT with CT angiography for acute ischemic stroke assessment.

Main Results:

  • p-CT is a fast, available, and reliable option for assessing cerebral perfusion.
  • p-CT is particularly useful in emergency settings for acute ischemic patients.
  • p-CT aids in diagnosing and managing cerebrovascular diseases and intracranial neoplasms.

Conclusions:

  • p-CT is a valuable tool for assessing cerebral perfusion and aiding in the diagnosis and management of various neurological conditions.
  • Its feasibility in emergency settings makes it crucial for acute ischemic stroke evaluation.
  • p-CT has diverse applications including functional reserve assessment and intracranial neoplasm management.