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Related Experiment Video

Updated: Jul 9, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
03:05

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia

Published on: February 16, 2024

[Pathologic worry].

Reinhard J Boerner1

  • 1Klinik für Psychiatrie und Psychotherapie CKQ, Zentrum für integrative Diagnostik u. Therapie von Angsterkrankungen (ZIDTA), Quakenbrück. r.boerner@christliches-krankenhaus-ev.de

MMW Fortschritte Der Medizin
|December 13, 2007
PubMed
Summary

Pathologic worry, a new term for anxiety disorders, is precisely measured by DANDTE and BOEAS scales. Effective treatments include pharmacotherapy with SSRI/SNRI and cognitive behavior therapy.

Area of Science:

  • Psychiatry and Psychology
  • Clinical Neuroscience

Background:

  • Pathologic worry is a key symptom in anxiety disorders, particularly Generalized Anxiety Disorder (GAD).
  • It is also a common feature in depression.
  • The classification of anxiety disorders now includes the term 'pathologic worry' in ICD-10 and DSM-IV.

Purpose of the Study:

  • To introduce and validate new assessment scales for pathologic worry.
  • To provide economic and precise tools for clinical routine assessment of anxiety symptoms.
  • To review current therapeutic options for anxiety disorders characterized by pathologic worry.

Main Methods:

  • Development and implementation of the DANDTE (self-Rating-Inventory) and BOEAS (observer Rating Scale).
  • Evaluation of the scales' precision and economic utility in clinical settings.

Related Experiment Videos

Last Updated: Jul 9, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
03:05

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia

Published on: February 16, 2024

  • Review of existing literature on pharmacotherapy and psychotherapy for anxiety disorders.

    • Main Results:

    • The DANDTE and BOEAS scales offer precise and economical assessment of pathologic worry and other anxiety symptoms.
    • Selective Serotonin Reuptake Inhibitors (SSRI) and Serotonin-Norepinephrine Reuptake Inhibitors (SNRI) are identified as first-line pharmacotherapies.
    • Other agents like Buspirone, Opipramol, and Pregabalin are viable options for short-term and long-term management.

    Conclusions:

    • The DANDTE and BOEAS scales are valuable tools for the clinical assessment of pathologic worry.
    • Pharmacological interventions, including SSRIs, SNRIs, Buspirone, Opipramol, and Pregabalin, are effective in managing anxiety disorders.
    • Cognitive behavior therapy presents a validated psychotherapeutic alternative for treating anxiety disorders.