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Updated: Jul 9, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
[Perinatal stroke--clinical validity of the ET 6-6]
Monika Daseking1, Julia Lemcke, Thorsten Macha
1Zentrum für Klinische Psychologie und Rehabilitation der Universität Bremen. daseking@uni-bremen.de
Insights
The ET 6-6 test effectively identifies developmental delays in children with perinatal stroke. Left-hemispheric strokes are associated with more significant impairments, highlighting the test
Area of Science:
- Pediatric Neurology
- Developmental Psychology
Context:
- Perinatal stroke impacts child development, necessitating accurate assessment tools.
- Early identification of developmental impairments is crucial for timely intervention.
Purpose:
- To evaluate the clinical utility of the Early Test 6-6 (ET 6-6) as a general developmental assessment for children with perinatal stroke.
- To determine if stroke localization influences the pattern of developmental difficulties.
Summary:
- 32 children (36-72 months) with perinatal stroke were assessed using the ET 6-6 and compared to controls.
- The study group demonstrated significantly lower developmental performance across most domains.
- Children with left-hemispheric strokes exhibited more severe impairments compared to those with right-hemispheric or basal ganglia strokes.
Impact:
- The ET 6-6 is a valuable tool for identifying developmental risks in children affected by perinatal stroke.
- Findings support the use of the ET 6-6 for targeted developmental evaluations based on stroke location.
Background:
The present study evaluates the role of the clinical use of the ET 6-6 as a general developmental test in assessing impairments following perinatal stroke.
Methods:
32 children aged 36 up to 72 months who had suffered a perinatal stroke were matched with a corresponding control group and assessed by means of the ET 6-6. A specification of developmental difficulties was evaluated according to the localisation of the stroke. Differences in performance were analyzed using nonparametric tests.
Results:
The study group showed a significantly lower level of performance in almost every dimension of development. Children with left-hemispheric stroke displayed greater developmental impairment than did children with right-hemispheric or basal ganglia stroke.
Conclusions:
These data suggest the applicability of the ET 6-6 in assessing developmental risks caused by perinatal stroke.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Ischemic Stroke l: Introduction

