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Routine pathological analysis of appendicectomy specimens--is it justified?
O A Khan1, A Morhan, S Jegatheeswaran
1Department of Surgery, St. Mary's Hospital, Isle of Wight, UK.
Acta Chirurgica Belgica
|December 14, 2007
Summary
Routine histological examination of appendicectomy specimens is valuable. Unexpected findings in appendicitis cases can alter medical therapy for a significant minority of patients.
Area of Science:
- Surgical Pathology
- Gastrointestinal Surgery
Background:
- Appendicectomy for acute appendicitis is a frequent surgical procedure.
- The necessity of routine pathological examination of appendicectomy specimens has been questioned.
Purpose of the Study:
- To evaluate the clinical utility of routine histological examination of appendicectomy specimens.
- To determine the rate of unexpected histological findings and their impact on patient management.
Main Methods:
- A review of 236 consecutive patients undergoing open appendicectomy for suspected appendicitis.
- Analysis of pathological and histological findings from resected appendicectomy specimens.
Main Results:
- Histological examination revealed inflammation or necrosis in 74% of cases.
- Unexpected histological findings were identified in 4.2% of specimens.
- These unexpected findings led to changes in medical therapy in 2.1% of patients.
Conclusions:
- Appendicectomy specimens exhibit diverse histological characteristics.
- Routine histological examination provides clinically significant information in a notable minority of patients with suspected appendicitis.
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