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Ethical problems with bioidentical hormone therapy.

M S Rosenthal1

  • 1Program for Bioethics and Patients' Rights, Department of Behavioral Science, University of Kentucky, College of Medicine, Lexington, KY 40536-0086, USA. msrose2@email.uky.edu

International Journal of Impotence Research
|December 14, 2007
PubMed
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Bioidentical hormone replacement therapy (BHRT) is often misunderstood and misrepresented. Current evidence does not support BHRT as superior to standard care, raising clinical and ethical concerns.

Area of Science:

  • Endocrinology
  • Medical Ethics
  • Pharmacology

Background:

  • The term 'bioidentical' hormone replacement therapy (BHRT) is frequently misunderstood by patients and misrepresented in available literature.
  • Prescribing practices for BHRT lack robust evidence supporting its superiority over standard care.
  • Concerns exist regarding the ethical implications of BHRT, including unregulated research and conflicts of interest.

Purpose of the Study:

  • To critically examine the clinical, research, and professional ethics issues surrounding bioidentical hormone replacement therapy (BHRT).
  • To address the widespread misunderstanding and misrepresentation of BHRT in patient education and clinical practice.

Main Methods:

  • Literature review and critical analysis of existing studies and ethical guidelines related to BHRT.

Related Experiment Videos

  • Examination of clinical trial data, regulatory oversight, and professional competency standards for BHRT prescribers.

    • Main Results:

    • BHRT is often promoted as innovative without peer-reviewed evidence of its efficacy compared to standard hormone replacement therapies.
    • Instances of unethical research involving high doses of hormones in BHRT have been noted.
    • Significant variability exists in the competencies of BHRT prescribers, with potential conflicts of interest arising from commercial promotion of BHRT formulations.

    Conclusions:

    • Bioidentical hormone replacement therapy (BHRT) presents significant clinical challenges and raises serious professional ethics concerns.
    • The lack of evidence-based support and ethical oversight necessitates a re-evaluation of BHRT practices and patient information.