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Human genome protein function database
1Dept. Medical Informatics, University of Utah, Salt Lake City.
Proceedings. Symposium on Computer Applications in Medical Care
|January 1, 1991
Summary
This study constructed a database detailing normal human protein functions, aiding biomedical research. The database facilitates protein classification and information retrieval for scientific discovery.
Area of Science:
- Bioinformatics
- Human Genomics
- Molecular Biology
Background:
- The Human Genome Project has identified numerous protein-coding genes.
- Understanding the normal functions of these proteins is crucial for biomedical research.
- Existing resources may lack comprehensive, integrated functional information.
Purpose of the Study:
- To construct a centralized database of human protein functions.
- To develop a program with advanced features for managing and accessing protein data.
- To classify human proteins based on their biomedical functions.
Main Methods:
- Database construction focusing on normal protein functions.
- Integration of diverse data formats including text, figures, tables, and diagrams.
- Development of a program with functionalities for data modification, updating, categorization, hypertext linking, searching, reporting, and inter-database linking.
- Utilization of a semi-automated categorization feature for functional classification.
Main Results:
- A comprehensive database of human protein functions was successfully created.
- The database program incorporates robust tools for data management and retrieval.
- Human proteins were systematically classified according to their biomedical functions using the developed system.
Conclusions:
- The constructed database provides a valuable resource for studying human protein functions.
- The database program enhances accessibility and utility of genomic and proteomic information.
- Systematic functional classification aids in advancing biomedical research and understanding human health and disease.