Estimation of entire cardiac left ventricular pressure cycle from brachial arterial pressure during systemic hypoxia

In functional study of the cardiac pump during systemic hypoxia, noninvasive measurement of the cardiac left ventricular pressure (LVP) during hypoxia is a tempting problem. The authors found from point of view of systems physiology that there existed correlation between brachial arterial blood pressure (BP) and LVP. Using method of normalization and stepwise regression, models were established for estimating LVP upon BP. For the LVP estimated with single hypoxia condition models the average relative area errors e less than 4.3%, with the general hypoxia condition model, e = 5.6%. This approach may be expected to be developed into a method of noninvasive measuring of the LVP.