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Updated: Jul 9, 2026

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection
Published on: October 7, 2021
Reproduction in Strongyloides (Nematoda): a life between sex and parthenogenesis
1Max Planck Institute for Developmental Biology, Department IV, Evolutionary Biology, Spemannstrasse 37, D-72076 Tübingen, Germany. adrian.streit@tuebingen.mpg.de
Abstract:
Nematodes of the genus Strongyloides parasitize the small intestines of vertebrates. In addition to a parasitic life-cycle, which is generally considered to be parthenogenetic, Strongyloides can also have a facultative, free-living generation involving male and female worms. The purpose of the present article was to review the literature on the modes of reproduction, the routes of development in the two generations of Strongyloides, discuss the controversial opinions in the literature regarding these aspects and point to new opportunities for addressing key questions in relation to the biology of reproduction of members of the genus employing genetic and genomic tools.
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