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Related Experiment Video

Updated: Jul 9, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Case report: Denys- Drash syndrome.

A B Ammari1, D E Fung

  • 1Child Dental Health Department, Royal Hospital for Sick Children, Glasgow, Scotland. amera.ammari@northglasgow.scot.nhs.uk

European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry
|December 14, 2007
PubMed
Summary

Denys-Drash Syndrome (DDS) management in a pediatric patient involved aesthetic dental rehabilitation for discolored teeth. Restorative treatments, including veneers and crowns, significantly improved the patient's satisfaction and oral appearance.

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Last Updated: Jul 9, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

  • Pediatric Dentistry
  • Dental Aesthetics
  • Syndrome Management

Background:

  • Denys-Drash Syndrome (DDS) is a rare genetic disorder characterized by congenital nephropathy, Wilms tumor, and intersex conditions.
  • DDS can manifest sporadically or as an autosomal dominant trait, typically presenting within the first year of life.

Observation:

  • A 10-year-old girl with DDS presented with severe dental discoloration, causing peer-related distress.
  • The patient had a history of dental anxiety and previous treatment under general anesthesia.

Findings:

  • Comprehensive dental rehabilitation included oral hygiene instruction, fluoride therapy, and placement of Dyract(AP) and BelleGlass NG veneers/crowns.
  • The patient reported sustained satisfaction with the aesthetic and functional outcomes of the restorative treatments over 27 months.

Implications:

  • Aesthetic dental rehabilitation can significantly improve the quality of life for children with DDS.
  • Multidisciplinary care involving pediatric nephrology and dentistry is crucial for managing complex cases like DDS.