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Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Published on: November 22, 2024
[Clinical forms of corneal abnormalities in atopic keratoconjunctivitis]
Abstract:
Atopic keratoconjunctivitis (AKC) is presently considered as an individual nosological entity of ocular allergosis, which is associated with the systemic disease - atopic dermatitis. The clinical features of corneal lesions were studied in 40 patients with AKC. Those associated with the systemic pattern of an atopic process as a severe form of ocular allergosis were revealed. A classification of the clinical forms of corneal lesions in AKC as limbitis, epithelial microerosions, epithelial keratopathy, superficial keratitis in mild forms of the disease, is presented. The severe forms of AKC were characterized by corneal manifestations: extensive keratopathy, stromal keratitis with neovascularization without ulceration, corneal infiltrates and ulcers of bacterial and herpetic etiology.
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