Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Executive function, mentalizing and humor in major depression.

J Uekermann1, S Channon, C Lehmkämper

  • 1Institute of Cognitive Neuroscience, Ruhr-University of Bochum, Germany. jennifer.ueckermann@ruhr-uni-bochum.de

Journal of the International Neuropsychological Society : JINS
|December 15, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond MDM2 amplification: chromosomal translocations as diagnostic drivers in adipocytic tumours-a histopathological and molecular reappraisal.

The Malaysian journal of pathology·2026
Same author

The SuPPORT project: Supporting Parents and Professionals through NeOnatal resuscitation in theatre. Phases 1 and 2: qualitative synthesis and capture of current practice.

International journal of obstetric anesthesia·2025
Same author

Hepatoprotective action of papain-hydrolyzed buffalo milk protein on carbon tetrachloride oxidative stressed albino rats.

Journal of dairy science·2019
Same author

[Quality of life and depression in hearing-impairment : A German survey].

HNO·2018
Same author

Perception of emotional prosody in adults with attention deficit hyperactivity disorder.

Acta psychiatrica Scandinavica·2017
Same author

Establishing the feasibility of a community and primary health care intervention to raise awareness of symptoms of Type 1 Diabetes-The Early Detection of Type 1 Diabetes in Youth (EDDY) study.

Pediatric diabetes·2017
Same journal

Preliminary evaluation of a novel Brief Mathematics Achievement Test as a proxy for measuring quality of education in culturally and linguistically diverse populations.

Journal of the International Neuropsychological Society : JINS·2026
Same journal

Cognitive dispersion in the Alzheimer's disease spectrum.

Journal of the International Neuropsychological Society : JINS·2026
Same journal

Randomized controlled trial of Understanding Social Situations versus problem-solving training in improving social function in people with psychosis.

Journal of the International Neuropsychological Society : JINS·2026
Same journal

Neuropsychological criteria for Mild Cognitive Impairment (MCI) best identify neuroimaging-based risk profiles: A Department of Defense/Alzheimer's Disease Neuroimaging Initiative study.

Journal of the International Neuropsychological Society : JINS·2026
Same journal

King-Devick test normative values and reliable change analysis for elite Finnish adolescent ice hockey athletes.

Journal of the International Neuropsychological Society : JINS·2026
Same journal

Age-varying associations between parent-reported executive function and internalizing/externalizing problems in children with neurofibromatosis type 1: an integrative analysis of data from nine institutions.

Journal of the International Neuropsychological Society : JINS·2026
See all related articles

Major depression is linked to social cognition deficits, impacting humor processing and mentalizing abilities. These impairments may affect social interactions and require consideration in depression treatment.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Major depression is characterized by cognitive deficits affecting memory and executive functions.
  • Frontostriatal network dysfunction is implicated in these cognitive impairments.
  • Social cognition, particularly humor processing, remains understudied in major depression.

Purpose of the Study:

  • To investigate social cognition deficits in major depression using a humor-processing task.
  • To examine the relationship between humor processing, theory of mind (mentalizing), and executive functions in depressed patients.

Main Methods:

  • A computerized humor-processing task was administered to 27 patients with major depression and 27 healthy controls.
  • Theory of mind (mentalizing) and executive functions were also assessed.

Related Experiment Videos

  • Groups were matched for IQ, age, and gender.

    • Main Results:

    • Depressed patients showed significant deficits in both affective and cognitive aspects of humor processing compared to controls.
    • Humor processing impairments were correlated with deficits in mentalizing and executive functions.
    • No significant differences were found between groups in IQ, age, or gender.

    Conclusions:

    • Major depression is associated with social cognition deficits, specifically in humor appreciation.
    • Impaired humor processing and mentalizing may contribute to social interaction difficulties in depression.
    • These findings suggest that social cognition should be considered in therapeutic interventions for major depression.