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Published on: December 16, 2022
Analysis of heart rate and heart rate variation during cardiac CT examinations
Jie Zhang1, Joel G Fletcher, W Scott Harmsen
1Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55455, USA.
Insights
Cardiac CT scans lower heart rate during breath-holds, but heart rate variability remains stable. This finding is crucial for optimizing cardiac computed tomography (CT) imaging quality and patient outcomes.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Physics
Background:
- Cardiac computed tomography (CT) requires precise imaging.
- Heart rate and its variability can impact image quality.
- Optimizing physiological parameters during CT is essential.
Purpose of the Study:
- To evaluate the effect of breath-holding during cardiac CT on heart rate and heart rate variability.
- To compare physiological parameters during different phases of cardiac CT acquisition.
Main Methods:
- Ninety patients underwent coronary CT angiography (CTA) and/or coronary artery calcium (CAC) scanning.
- Heart rate and heart rate variability were measured during baseline (free breathing), hyperventilation, and breath-hold scan acquisition.
- Patients received beta-blockers or nitroglycerin as needed.
Main Results:
- Mean heart rate was significantly lower during scan acquisition (58-59 bpm) compared to baseline (63 bpm) (P < .001).
- Heart rate variability, measured as percentage of beats outside +/-5 bpm, showed no significant difference between baseline and scan acquisition (3.5% vs 3.3%, P = .87).
- Contrast injection did not significantly affect heart rate or variability.
Conclusions:
- Breath-holding during cardiac CT acquisition effectively reduces mean heart rate.
- Heart rate variability remains comparable or is reduced during breath-holding compared to normal breathing.
- These findings suggest breath-holding is beneficial for cardiac CT without compromising heart rate stability.
Rationale And Objectives:
We sought to examine heart rate and heart rate variability during cardiac computed tomography (CT).
Materials And Methods:
Ninety patients (59.0 +/- 13.5 years) underwent coronary CT angiography (CTA), with 52 patients also undergoing coronary artery calcium scanning (CAC). Forty-two patients with heart rate greater than 70 bpm were pretreated with oral beta-blockers (in five patients, use of beta-blocker was not known). Sixty-four patients were given sublingual nitroglycerin. Mean heart rate and percentage of beats outside a +/-5 bpm region about the mean were compared between baseline (free breathing), prescan hyperventilation, and scan acquisition (breath-hold).
Results:
Mean scan acquisition time was 13.1 +/- 1.5 seconds for CAC scanning and 14.2 +/- 2.9 seconds for coronary CTA. Mean heart rate during scan acquisition was significantly lower than at baseline (CAC 58.2 +/- 8.5 bpm; CTA 59.2 +/- 8.8 bpm; baseline 62.8 +/- 8.9 bpm; P < .001). The percentage of beats outside a +/-5 bpm about the mean were not different between baseline and CTA scanning (3.5% versus 3.3%, P = .87). The injection of contrast had no significant effect on heart rate (58.2 bpm versus 59.2 bpm, P = .24) or percentage of beats outside a +/-5 bpm about the mean (3.0% versus 3.3%, P = .64). No significant difference was found between gender and age groups (P > .05).
Conclusions:
Breath-holding during cardiac CT scan acquisition significantly lowers the mean heart rate by approximately 4 bpm, but heart rate variability is the same or less compared with normal breathing.
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