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Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Obstructive sleep apnea and resistant hypertension: a case-control study.

Sandro Cadaval Gonçalves¹, Denis Martinez, Miguel Gus

¹Division of Cardiology and Postgraduate Program in Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

|December 15, 2007

Summary

Obstructive sleep apnea syndrome (OSAS) is a significant risk factor for resistant hypertension. Early consideration of OSAS in patients with difficult-to-treat hypertension is crucial for effective management.

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Last Updated: Jul 9, 2026

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Area of Science:

Cardiology
Sleep Medicine
Hypertension Research

Background:

Obstructive sleep apnea syndrome (OSAS) is suspected to be linked with resistant hypertension.
However, the extent of this association and its independence from confounding factors remain unclear.

Purpose of the Study:

To determine the association between OSAS and resistant hypertension.
To evaluate if OSAS is an independent risk factor for resistant hypertension.

Main Methods:

A case-control study involving 63 patients with resistant hypertension and 63 controls with controlled blood pressure.
OSAS diagnosis was based on apnea-hypopnea index (AHI) using a portable home monitor.
Secondary analysis compared AHI across different hypertension phenotypes using ambulatory blood pressure monitoring (ABPM).

Main Results:

OSAS was significantly more prevalent in patients with resistant hypertension (71%) compared to controls (38%) (p < 0.001).
OSAS demonstrated a strong, independent association with resistant hypertension (OR, 4.8; 95% CI, 2.0 to 11.7).
AHI levels varied significantly across different blood pressure categories, including white coat and masked hypertension.

Conclusions:

The findings confirm OSAS as a significant and independent risk factor for resistant hypertension.
Clinicians should consider screening for comorbid OSAS in patients diagnosed with resistant hypertension.