Related Experiment Video
Updated: Oct 12, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
Published on: June 6, 2025
[Antidepressive treatments. Predictive factors of tolerability]
1Service du Pr Lôo, Hôpital Sainte-Anne, Paris.
Abstract:
Conducting an antidepressant treatment supposes the analysis of various parameters concerning patients, depressive illness and psychotropic drugs. The first determinant of prescription is the expected antidepressant effect. But regarding the role of compliance in the efficacy of treatment, probable tolerability also plays a role. It remains difficult to predict tolerability. A questionnaire was designed to assess the relevance of various predictive factors taken into account in the prognosis of tolerability: global tolerability, patient's psychopathological structure, clinical aspects of depression and characteristics of the particular antidepressant being used.
More Related Videos
Related Concept Videos
Factors Affecting Drug Response: Overview
Antidepressant Drugs: Overview
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Antidepressant Drugs: MAOIs and Other Agents
Therapeutic Drug Monitoring: Affecting Factors
Drug Toxicity: Risk factors

