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Updated: Jul 9, 2026

Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy (Conpokal) on Live Cells
Published on: August 11, 2020
Past, present and future of atomic force microscopy in life sciences and medicine
Pierre Parot1, Yves F Dufrêne, Peter Hinterdorfer
1CEA-Valrhô DSV/iBEB/SBTN, 30207 Bagnols sur Cèze Marcoule, France. parot@cea.fr <parot@cea.fr>
Abstract:
To introduce this special issue of the Journal of Molecular Recognition dedicated to the applications of atomic force microscopy (AFM) in life sciences, this paper presents a short summary of the history of AFM in biology. Based on contributions from the first international conference of AFM in biological sciences and medicine (AFM BioMed Barcelona, 19-21 April 2007), we present and discuss recent progress made using AFM for studying cells and cellular interactions, probing single molecules, imaging biosurfaces at high resolution and investigating model membranes and their interactions. Future prospects in these different fields are also highlighted.
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