Multisession CyberKnife radiosurgery for optic nerve sheath meningiomas

Area of Science:

• Neurosurgery
• Radiation Oncology
• Ophthalmology

Background:

• Optic nerve sheath meningiomas (ONSMs) are benign tumors arising from the optic nerve's dural sheath.
• Tumor progression can cause vision loss and exophthalmos.
• Current treatments like microsurgery and fractionated radiotherapy have limitations, including potential vision loss and complications.

Purpose of the Study:

• To review the clinical presentation and management of ONSMs.
• To describe the preliminary experience with multisession radiosurgery for ONSMs.
• To evaluate the efficacy and safety of frameless radiosurgery for ONSMs.

Main Methods:

• Review of clinical presentation and management strategies for ONSMs.
• Preliminary experience with multisession, image-guided radiosurgery using the CyberKnife system.
• Assessment of tumor control and vision preservation in patients treated with CyberKnife.

Main Results:

• Frameless radiosurgery, such as CyberKnife, offers high conformality and accuracy.
• Multisession radiosurgery may be a viable alternative for ONSM treatment.
• Preliminary data suggests potential for tumor growth control and vision preservation.

Conclusions:

• Multisession radiosurgery with frameless systems like CyberKnife is a promising treatment option for ONSMs.
• This approach may offer a safer alternative to traditional methods, with reduced toxicity.
• Further investigation is warranted to establish long-term outcomes.