Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stereotactic radiosurgery for functional disorders.

Gerhard M Friehs1, Michael C Park, Marc A Goldman

  • 1Department of Clinical Neurosciences Program in Neurosurgery and New England Gamma Knife Center, Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island, USA. gfriehs@yahoo.com

Neurosurgical Focus
|December 18, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating dorsal root ganglion stimulation with transforaminal lumbar interbody fusion: proof of concept study.

North American Spine Society journal·2026
Same author

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy.

Epilepsia·2026
Same author

A novel methodology for localizing pallidal deep brain stimulation leads.

Frontiers in neuroanatomy·2026
Same author

Tumor antigen only (TAO) vaccine platforms for glioblastoma therapeutics: a systematic review of evidence from clinical trials.

EClinicalMedicine·2026
Same author

Race, socioeconomic status, and geography influence utilization of surgery in Minnesota epilepsy patients.

Journal of neurosurgery·2026
Same author

An Integrated Dataset of Metastatic Breast Cancer to the Brain with Imaging, Radiomics, and Tumor Genetics.

Scientific data·2025
Same journal

Letter to the Editor. Enhancing comparability in idiopathic intracranial hypertension research through standardized outcome measures.

Neurosurgical focus·2026
Same journal

Introduction. Contemporary spinal arthroplasty.

Neurosurgical focus·2026
Same journal

Cervical disc arthroplasty as a safe and effective procedure for obese patients.

Neurosurgical focus·2026
Same journal

Comparing the operational metrics and functional outcomes of lumbar arthroplasty implants: a systematic review.

Neurosurgical focus·2026
Same journal

Long-term reoperation risk after cervical disc arthroplasty versus fusion: a level-matched meta-analysis of FDA investigational device exemption studies and international randomized trials.

Neurosurgical focus·2026
Same journal

Total disc replacement versus lumbar interbody fusion for degenerative disc disease: a meta-analysis of randomized controlled trials.

Neurosurgical focus·2026
See all related articles

Stereotactic radiosurgery (SRS) offers a noninvasive option for brain disorders, primarily tumors and AVMs. While effective for functional indications like tremor and pain, it has limitations in targeting accuracy and potential complications.

Area of Science:

  • Neurosurgery
  • Radiation Oncology

Background:

  • Stereotactic radiosurgery (SRS) has transformed neurosurgery over two decades.
  • Current primary uses include brain tumors and arteriovenous malformations.
  • Functional indications represent a smaller patient subset.

Purpose of the Study:

  • To review the current applications and limitations of SRS in neurosurgery.
  • To highlight functional indications and emerging uses of SRS.

Main Methods:

  • Review of current clinical practices and literature regarding SRS.
  • Analysis of indications, outcomes, and challenges in functional radiosurgery.

Main Results:

  • SRS is predominantly used for tumors and AVMs.

Related Experiment Videos

  • Functional indications include trigeminal neuralgia, tremor, and investigational epilepsy/psychiatric conditions.
  • Radiosurgical pallidotomy/medial thalamotomy is discouraged; ventrolateral thalamotomy for tremor is an option for select patients.
  • High-dose radiosurgery to the pituitary stalk shows promise for intractable cancer pain.

    • Conclusions:

    • SRS is a valuable noninvasive tool in neurosurgery, with established roles and evolving applications.
    • Limitations in targeting and potential complications necessitate careful patient selection for functional SRS.
    • Emerging applications, such as pituitary stalk radiosurgery, offer new hope for severe pain management.