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Hirsutism.
A Mofid1, S A Seyyed Alinaghi, S Zandieh
1Department of Internal Medicine, Tehran University of Medical Sciences, Sina Hospital, Tehran, Iran. mofid@tums.ac.ir
International Journal of Clinical Practice
|December 18, 2007
Summary
Hirsutism, excessive hair growth in women, is often linked to hyperandrogenemia. Effective treatment involves combination therapy addressing the underlying cause and may require lifelong management for sustained results.
Area of Science:
- Endocrinology
- Dermatology
- Gynecology
Background:
- Hirsutism is defined as excessive terminal hair growth in women, following a male pattern.
- It is a common condition with significant psychological impact, often triggered by hyperandrogenemia.
- Polycystic ovary syndrome and idiopathic hirsutism are the most frequent causes.
Purpose of the Study:
- To review the definition, pathogenesis, and differential diagnosis of hirsutism.
- To outline diagnostic strategies and management guidelines for hirsutism.
- To provide recommendations for the effective treatment of hirsutism.
Main Methods:
- Comprehensive review of existing literature on hirsutism.
- Analysis of diagnostic criteria and investigation pathways.
- Evaluation of current treatment modalities and therapeutic strategies.
Main Results:
- Hyperandrogenemia is identified as the primary driver of hirsutism.
- A serum testosterone level exceeding 150 ng/dl warrants investigation for androgen-secreting tumors.
- Combination therapy, including lifestyle changes and hormonal treatments, is most effective.
Conclusions:
- Hirsutism management requires a thorough diagnostic approach to identify the underlying cause.
- Combination therapy offers the best outcomes, but patients must be counseled on the timeline for improvement and potential need for lifelong treatment.
- Early and appropriate intervention can mitigate the psychological distress associated with hirsutism.
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