Lifetime basilar migraine: a pontine syndrome?
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Updated: Jul 9, 2026

Establishment of Acute Pontine Infarction in Rats by Electrical Stimulation
Published on: August 27, 2020
Nishant Kumar Mishra1, Carlo Cereda, Antonio Carota
1Department of Neurology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
Abstract:
We describe the clinical and radiological findings of an 82-year-old woman patient with basilar type migraine attacks occurring over 70 years with a similar pattern of intensity and symptoms. We provide some evidence to suggest that gradual development of calcifications in the pontine tegmental nuclei can trigger attacks of basilar type migraine.
Insights
Basilar type migraine attacks, lasting over 70 years, were observed in an 82-year-old woman. Calcifications in the pontine tegmental nuclei may trigger these chronic basilar type migraine attacks.
Area of Science:
- Neurology
- Neuroimaging
- Geriatric Medicine
Background:
- Basilar type migraine is a rare subtype of migraine characterized by neurological symptoms originating in the brainstem.
- Chronic migraine conditions require thorough investigation into potential underlying causes, especially in elderly patients.
Observation:
- An 82-year-old female patient experienced basilar type migraine attacks for over seven decades with consistent symptom patterns.
- Clinical and radiological assessments were performed to investigate the persistent migraine episodes.
Findings:
- The patient exhibited gradual development of calcifications within the pontine tegmental nuclei.
- Evidence suggests a correlation between these pontine tegmental nuclei calcifications and the triggering of basilar type migraine attacks.
Implications:
- This case highlights a potential novel mechanism for basilar type migraine, involving pontine tegmental nuclei calcifications.
- Further research into neuroimaging findings and calcification development may offer new diagnostic and therapeutic strategies for chronic migraine subtypes.
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