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[Comparison of clinical data of childhood asthma in different periods in Changsha]

Yun Li1, Tang Wang, Han Huang

  • 1Department of Pediatrics, Hunan People's Hospital, Changsha, China. liyunpd@21.cn.com

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|December 18, 2007
PubMed

Insights

Childhood asthma cases increased over 20 years, with more allergic rhinitis and better treatment outcomes using inhaled glucocorticoids. Asthmatic children are also more likely to attend follow-up appointments.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Clinical Medicine

Background:

  • Childhood asthma incidence is rising globally.
  • Understanding changes in clinical presentation and treatment efficacy is crucial for managing pediatric asthma.
  • A 20-year retrospective analysis provides insight into evolving asthma management.

Purpose of the Study:

  • To investigate the changes in clinical features of childhood asthma over a two-decade period.
  • To compare treatment outcomes between different therapeutic approaches.
  • To assess trends in associated allergic conditions and patient compliance.

Main Methods:

  • Retrospective analysis of medical data from 400 children with asthma, divided into two groups (1986-1988 and 2005-2006).
  • Comparison of clinical characteristics, including allergic rhinitis, exercise-induced asthma, drug allergy, and irritant-induced asthma.
  • Evaluation of treatment strategies and their efficacy in controlling asthma symptoms.

Main Results:

  • A significant increase in concomitant allergic rhinitis was observed (33.5% vs. 64.0%).
  • Higher incidence of exercise-induced asthma, drug allergy, and irritant-induced asthma in the later cohort.
  • Improved asthma control rates (37.9% vs. 83.0%) with inhaled glucocorticoid therapy compared to nonspecific immune therapy.

Conclusions:

  • The incidence of allergic comorbidities in childhood asthma has increased over 20 years.
  • Increased compliance with re-examinations and the efficacy of inhaled glucocorticosteroid therapy contribute to better asthma management.
  • Evolving treatment strategies have led to improved outcomes in pediatric asthma patients.
Abstract

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