Dolasetron-induced torsades de pointes
Related Experiment Video
Updated: Jul 9, 2026

High-Definition Transcranial Direct Current Stimulation During Sleep
Published on: December 5, 2025
Sarah Turner1, Letha Mathews, Pratik Pandharipande
1Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN 37212, USA. thesooner@aol.com
Abstract:
A 52-year-old woman with hypertension and Graves' disease was scheduled for surgical removal of a meningioma. Intraoperative events were significant for hypotension requiring a vasopressin infusion. Prophylactic dolasetron was administered to the patient before emergence. The patient's trachea was easily extubated and she was neurologically intact at the end of the surgical procedure. On transport to the neurological intensive care unit, the patient developed torsades de pointes, requiring cardiopulmonary resuscitation, before a return to normal sinus rhythm.
Related Concept Videos
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Depolarizing Blockers: Pharmocokinetics
Desensitization and Tachyphylaxis
Several...
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...

