Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cognitive function in children and subsequent type 2 diabetes.

Gunilla M Olsson1, Anna-Lena Hulting, Scott M Montgomery

  • 1Neuroscience, Uppsala University, Uppsala, Sweden. gunilla.olsson@neuro.uu.se

Diabetes Care
|December 18, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Remission, complications, and overall survival in transsphenoidal pituitary surgery-a Swedish single-center experience of 578 patients.

Acta neurochirurgica·2023
Same author

GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility.

Nature communications·2021
Same author

Evaluation of different hydrocortisone treatment strategies in transsphenoidal pituitary surgery.

Acta neurochirurgica·2019
Same author

Long-term follow-up after cure from chronic hepatitis C virus infection shows occult hepatitis and a risk of hepatocellular carcinoma in noncirrhotic patients.

European journal of gastroenterology & hepatology·2018
Same author

Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden.

Scientific reports·2018
Same author

Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1.

The Journal of clinical endocrinology and metabolism·2017
Same journal

30-Year Trends in Microvascular Complications and Treatment in Adolescents With Type 1 Diabetes.

Diabetes care·2026
Same journal

Reactive Hypoglycemia as a Transient Metabolic Phenotype of Stage 1 and 2 Type 1 Diabetes.

Diabetes care·2026
Same journal

Type 1 Diabetes Driven by Residual Recipient T Cells After Hematopoietic Cell Transplantation: A Case Report.

Diabetes care·2026
Same journal

Predicting the Path to Attrition: Multidomain Risk Assessment in Diabetic Foot Ulcer Offloading Randomized Controlled Trials.

Diabetes care·2026
Same journal

Habituation to Elevated Glucose Levels in Type 1 Diabetes: Function and Well-Being in Guideline-Based Versus Typical Glycemic Range.

Diabetes care·2026
Same journal

The Correlation Between Fear and Perceived Frequency of Hypoglycemia and Continuous Glucose Monitoring Metrics in Adults With Type 1 Diabetes Using Diabetes Technology: A One-Year Analysis.

Diabetes care·2026
See all related articles

Children with lower cognitive abilities, including general ability and reading comprehension, had a higher risk of developing type 2 diabetes later in life. This suggests cognitive function may precede diabetes diagnosis.

Area of Science:

  • Cognitive science
  • Epidemiology
  • Public Health

Background:

  • Type 2 diabetes is a growing global health concern.
  • Early identification of risk factors is crucial for prevention.
  • The relationship between childhood cognition and adult type 2 diabetes is not fully understood.

Purpose of the Study:

  • To investigate the association between childhood cognitive function and the diagnosis of type 2 diabetes by age 42.
  • To determine if cognitive deficits in childhood predict later type 2 diabetes.

Main Methods:

  • Utilized logistic regression analysis on data from 9,113 participants in the 1958 British birth cohort (National Child Development Study).
  • Assessed cognitive function using general ability and reading comprehension tests at age 11 years.

Related Experiment Videos

  • Adjusted for early-life exposures, family characteristics, sex, disability, and childhood BMI.

    • Main Results:

    • Lower general ability at age 11 was associated with a 33% reduced odds of type 2 diabetes diagnosis by age 42 (OR 0.67, 95% CI 0.51-0.87).
    • Lower reading comprehension at age 11 was associated with a 42% reduced odds of type 2 diabetes diagnosis by age 42 (OR 0.58, 95% CI 0.44-0.77).
    • These associations remained significant after adjusting for childhood BMI and were robust to later onset definitions of type 2 diabetes.

    Conclusions:

    • Impaired cognitive function in childhood, specifically in general ability and reading comprehension, is associated with an increased risk of developing type 2 diabetes.
    • Cognitive deficits may serve as an early indicator or precede the clinical manifestation of type 2 diabetes.
    • These findings highlight the potential role of cognitive function in the developmental trajectory of type 2 diabetes.